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Noninvasive Monitoring of Carbon Dioxide During Mechanical Ventilation in Older Children: End-Tidal Versus Transcutaneous Techniques
Berkenbosch J, et al. Anesthesia & Analgesia. 2001.
Transcutaneous CO2 monitoring provided an accurate estimation of PaCO2 over a wide range of CO2 values and was superior to etCO2 monitoring in older pediatric patients with respiratory failure.
Superiority of transcutaneous CO2 over end-tidal CO2 measurements for monitoring respiratory failure in nonintubated patients: A pilot study
Lermuzeaux, M, et al. Journal of Critical Care. 2016.
Large differences were found between etCO2 and PaCO2 in spontaneously breathing nonintubated ICU patients admitted for acute respiratory failure. The study argues against the use of etCO2 monitoring in such patients but raises the possibility that PtcCO2 measurement may provide reasonable estimates
Continuous non-invasive PCO2 monitoring in weaning patients: Transcutaneous is advantageous over end-tidal PCO2
Schwarz S, et al. Respirology. 2017.
"Our data therefore support PtcCO2 as a suitable means for monitoring PCO2 in patients undergoing invasive MV. This is in contrast to PetCO2, which clearly underestimated PaCO2, especially in patients with COPD."
Validation of a New Transcutaneous tcPO2/tcPCO2 Sensor with an Optical Oxygen Measurement in Preterm Neonates
van Weteringen, et al. Neonatology. 2020
This study of transcutaneous measurement in preterm neonates "found tcPCO2 remained accurate under all circumstances"
Transcutaneous CO2 versus end-tidal CO2 in neonates and infants undergoing surgery
Chandrakantan A, et al. Medical Devices: Evidence and Research. 2019.
These authors conclude that transcutaneous CO2 monitoring “is a more accurate measure of operative PvCO2 in infants, especially in NICU patients” compared to end-tidal.
Intrapulmonary percussive ventilation for children with bronchiolitis on non-invasive ventilation support
Cavari, Y., et al. Open Journal of Pediatrics and Child Health. 2022.
In this single-center study of ventilated children under 2 with severe bronchiolitis, “the use of IPV [therapy] had no adverse reactions.”
Comparison of intrapulmonary percussive ventilation and chest physiotherapy. A pilot study in patients with cystic fibrosis
Natale, J.E., et al. Chest. 1994.
Cystic fibrosis patients treated with IPV therapy did not experience adverse consequences and “reported no discomfort… compared with conventional P&PD [CPT] therapy.”
Intrapulmonary percussive ventilation vs incentive spirometry for children with neuromuscular disease
Reardon, C.C., et al. The Archives of Pediatrics & Adolescent Medicine. 2005.
"Intrapulmonary percussive ventilation as part of a preventive pulmonary regimen reduced days of antibiotic use and hospitalization for respiratory illness."
A comparison of the therapeutic effectiveness of and preference for postural drainage and percussion, intrapulmonary percussive ventilation, and high-frequency chest wall compression in hospitalized cystic fibrosis patients
Varekojis, S.M., et al. Respiratory Care. 2003.
"Participants [cystic fibrosis patients] thought they performed more bronchopulmonary hygiene with IPV therapy, spent less time on therapy, relied less on others for therapy, and thought IPV therapy was relatively comfortable."
A comparison of intrapulmonary percussive ventilation and conventional chest physiotherapy for the treatment of atelectasis in the pediatric patient
Deakins, K., et al. Respiratory Care. 2002.
This study found IPV therapy was more effective than CPT in reducing atelectasis in pediatric patients, improving atelectasis scores significantly (from 3 to 1, p < 0.001) and requiring less treatment time (2.1 vs. 6.2 days, p = 0.018).
