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Validation of a New Transcutaneous tcPO2/tcPCO2 Sensor with an Optical Oxygen Measurement in Preterm Neonates
van Weteringen, et al. Neonatology. 2020
This study of transcutaneous measurement in preterm neonates "found tcPCO2 remained accurate under all circumstances"
Transcutaneous CO2 versus end-tidal CO2 in neonates and infants undergoing surgery
Chandrakantan A, et al. Medical Devices: Evidence and Research. 2019.
These authors conclude that transcutaneous CO2 monitoring “is a more accurate measure of operative PvCO2 in infants, especially in NICU patients” compared to end-tidal.
Intrapulmonary percussive ventilation for children with bronchiolitis on non-invasive ventilation support
Cavari, Y., et al. Open Journal of Pediatrics and Child Health. 2022.
In this single-center study of ventilated children under 2 with severe bronchiolitis, “the use of IPV [therapy] had no adverse reactions.”
Comparison of intrapulmonary percussive ventilation and chest physiotherapy. A pilot study in patients with cystic fibrosis
Natale, J.E., et al. Chest. 1994.
Cystic fibrosis patients treated with IPV therapy did not experience adverse consequences and “reported no discomfort… compared with conventional P&PD [CPT] therapy.”
Intrapulmonary percussive ventilation vs incentive spirometry for children with neuromuscular disease
Reardon, C.C., et al. The Archives of Pediatrics & Adolescent Medicine. 2005.
"Intrapulmonary percussive ventilation as part of a preventive pulmonary regimen reduced days of antibiotic use and hospitalization for respiratory illness."
A comparison of the therapeutic effectiveness of and preference for postural drainage and percussion, intrapulmonary percussive ventilation, and high-frequency chest wall compression in hospitalized cystic fibrosis patients
Varekojis, S.M., et al. Respiratory Care. 2003.
"Participants [cystic fibrosis patients] thought they performed more bronchopulmonary hygiene with IPV therapy, spent less time on therapy, relied less on others for therapy, and thought IPV therapy was relatively comfortable."
A comparison of intrapulmonary percussive ventilation and conventional chest physiotherapy for the treatment of atelectasis in the pediatric patient
Deakins, K., et al. Respiratory Care. 2002.
This study found IPV therapy was more effective than CPT in reducing atelectasis in pediatric patients, improving atelectasis scores significantly (from 3 to 1, p < 0.001) and requiring less treatment time (2.1 vs. 6.2 days, p = 0.018).
Intrapulmonary percussive ventilation in tracheostomized patients: a randomized controlled trial
Clini, E.M., et al. Intensive Care Medicine. 2006.
In adult tracheostomized patients, researchers in this study found “all patients included in the intervention group tolerated [IPV therapy] very well.”
Predicting extubation failure after successful completion of a spontaneous breathing trial
Mokhlesi, B., et al. Respiratory Care. 2007.
"Patients with moderate or abundant secretions were 3–8 times more likely to fail extubation than those with few to no secretions."
Efficacy and safety of intrapulmonary percussive ventilation superimposed on conventional ventilation in obese patients with compression atelectasis
Tsuruta, R., et al. Journal of Critical Care. 2006.
IPV therapy helps recruit the lungs quickly for a wide variety of patients, as evidenced in this study which shows improvement in dynamic compliance and PAO2/FIO2 in patients with compression atelectasis.
